Sentence examples for a variant protein from inspiring English sources

Furthermore, the effects of a genetic variation may be indirect where an ADR emerges secondary to the interaction of a variant protein and a ligand perturbed wild type protein.

The dominant surface antigen of Borrelia is a variant protein encoded by a large repertoire of genes, only one of which is expressed at anyone time.

Such a silencing mechanism to prevent inappropriate expression of a variant protein gene has not been reported previously for Borreliae [ 6, 27, 28] and may be unique to B. recurrentis.

Weibezahn et al [ 64] engineered a ClpB variant termed BAP (ClpB-ClpP-loop; a variant protein in which ClpP interacting site of ClpA has been engineered into E. coli ClpB), which carried the P-element.

This is a hypomorphic mutation encoding a TGFBR1 variant protein with reduced TGF-β growth inhibition-signalling activity.

Indeed, each mutant allele produces a G6PD variant protein that, compared to normal G6PD, has a distinct pattern of quantitative and qualitative changes.

Our findings in Fgfr4 KO mice as well as using a FGF19 variant protein with reduced FGFR4 activity have delineated pathways downstream of FGF19.

Last, stopped flow FTIR spectroscopy was used to examine diatomic ligand formation using both the wild-type enzyme and a C394S/C397S variant protein.

These findings suggest that CD44v6 is an essential variant protein for metastatic cell growth in the host organ (Kaya et al, 1997).

Several flavors of histone H3 are expressed in higher eukaryotes including histone H3.1, H3.2, H3.3, and a centromere-specific H3 variant protein, CENP-A.

Together with one deficient result from an in silico assay, a decrease in variant protein expression, interaction, or localization was considered to be an indication of pathogenicity.