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They further thank Boris Freidlin, Paula Williamson and Ruwanthi Kolamunnage Dona for their valuable elucidations and for sharing their R code for generating correlated survival times.
NMR has proven to be a valuable tool in the elucidation of various properties for many of these proteins, allowing versatile studies of structure, dynamics, and interactions in the solution state.
The oligodendroglioma model presented here is a valuable model for further functional elucidation of the effects of IDH1 mutations on tumor metabolism and may aid in the rational development of novel therapeutic strategies for the large subgroup of gliomas carrying IDH1 mutations.
The zebrafish is a valuable vertebrate model system for the elucidation of novel molecular pathways of aging as well as early development [60].
This is clearly the most comprehensive book on computer-assisted structure elucidation on the market and generally a valuable resource for anyone working in the area of structure elucidation of small molecules.
The breed associated clinical features and chromosomal aberrations of canine HS offer a valuable spontaneous model for the human counterpart, aiding elucidation of the pathophysiological and genetic mechanisms associated with histiocytic malignancies and providing new opportunities for developing effective therapeutic modalities for both species.
Importantly, these draft genome sequences provided a valuable resource for identification of putative virulence factors and elucidation of possible pathogenicity mechanisms [ 18, 19].
The breed associated clinical features and DNA copy number aberrations exhibited by canine HS offer a valuable model for the human counterpart, providing additional evidence towards elucidation of the pathophysiological and genetic mechanisms associated with histiocytic malignancies.
Furthermore, the crystal structure of mouse KLK7 complexed with 22g enabled the elucidation of structure activity relationships and justified 22g as a valuable compound to overcome the species differences.
Thus, use of P. putida for expression of PKS/NRPS systems can be considered as a valuable option for the identification of high-value compounds and the elucidation of their biosynthetic pathways.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com