There have been many large national and international efforts that have led to a well-established validation methodology comprising analytical, inter-program comparison and empirical validation elements, and a significant number of tests have been developed.
The included validation elements are described in an appendix to the Mega-QI final report (Mega QI Report Appendix F, accessible at http://interrai.org/user_files/images/File/CMS%20%20-%20 %20-%20 %20Final %20Report %20Appendix %20F %2012 %20NOV
The framework of the Burn-up Credit Criticality Benchmark NEA-6227 (Phase II-D) is used to model different rodded configurations of a UO2 fuel assembly by the lattice code APOLLO2.8, providing also additional validation elements for the code.
Because Mega QI validation elements were collected via chart review and care giver interview for a select and focused set of QIs, requisite preventive or responsive care practices necessary to provide validity evidence for the expansive and broad set of QIs studied here may not be represented.
User requirements are usually used as validation elements at the end of the product design process.
Potential validation elements were categorized by quality of care construct along two dimensions: preventive and responsive.
As reported elsewhere [ 4], validation procedures for the original 21 QIs targeted by the Mega QI validation study involved expert clinical panel review of potential validation elements.
Missing data among validation elements were handled with single imputation using the method of chained linear regression equations with hot deck replacement prior to the PCA procedure [ 22].
These validation elements were then classified as preventive strategies (actions designed to prevent quality problems), or responsive strategies (actions initiated in response to the identification of quality problems).
Examining the estimation procedure for r GEBV we found that the increase was due to smaller estimates of the diagonal elements of the genomic relationship matrix between the validation elements (G V) in the scenario with all imputed genotypes.
Subsequent field testing of the designed composite training round served as a validation of the finite element models developed.
