A prospective validating trial is currently ongoing.
Validated trials, from trusted sources are essential.
The cavitated dentin lesions were randomly assigned to one of the treatment groups after stratification for gender, operator, upper/lower jaw and, when needed, according to left/right side of the mouth using a validated computer software program (Trial Balance, Lausanne, Switzerland).
A recent subanalysis of the phase IIIb ARRIVE (Abatacept Researched in Rheumatoid Arthritis Patients with an Inadequate Response to Validate Effectiveness) trial indicates that a wash-out period is not required before initiating abatacept in patients who have failed anti-TNF treatment (Schiff et al. 2007).
We therefore suggest validating in a prospective trial the AUC as a surrogate marker to tailor sorafenib dose adjustments, thereby avoiding increasing sorafenib dose until intolerable toxicity.
A prospective trial to validate these thresholds is needed.
Then, the approach and models were validated using a clinical trial data set.
A brief measure of perceived understanding of informed consent in a clinical trial was validated.
A clinical trial to validate our online personalization model is presented in Section 5. Section 6 discusses the experimental results, and we conclude in Section 7. Consider a hearing aid (HA) algorithm, where and are the input and output signals, respectively, and is a vector of tuning parameters, such as time constants and thresholds.
Currently, several prognostic microarray gene expression signatures for breast cancer have been generated using fresh frozen material [17] [25] and one of them is being validated in a prospective trial [26].
However, the implications of ALDH1 expression in RC should be validated in a clinical trial.
