16 The same group of international experts developed a validated grading scale for melomental folds (marionette lines), the marionette line grading scale.
The abdominal aorta calcification (AAC) score was calculated using a previously validated grading system, in which the extent of calcific deposits in the abdominal aorta is graded on a per segment basis [ 25].
Hyperintense regions within the paraspinal muscles observed on T2 axial images were considered fatty tissue [ 15] and categorised based on a previously validated grading method; grade 0: no fat, grade 1: 1 to 10% fat, grade 2: 11 to 50% fat and grade 3: >50% fat [ 15].
Using an empirically derived and validated grading system, severity is divided into five categories: grade 0 (pain free), grade 1 (low disability, low-pain intensity), grade 2 (low disability, high-pain intensity); grade 3 (high disability, moderately limiting pain); and grade 4 (high disability, severely limiting pain).
To develop and validate grading scales for meibomian gland dysfunction (MGD) that allow consistent diagnosis of MGD and are suitable for clinical studies.
Third, our competitions used validated grading system to score the results.
"This is a validating group.
Pathologic response to neoadjuvant chemotherapy was graded by clinical pathologists upon resection using a validated scale [ 27].
The demonstration of the stepwise increase in the likelihood of malignancy between lesions of different imaging grade and the significant differences between these grades validates the grading scheme adopted by the Royal Australian and New Zealand College of Radiologists.
The grade of aortic arch calcification was assessed using a previously validated scoring system: grade 0 (no visible calcification), grade 1 (small spots of calcification or single thin calcification of the aortic knob), grade 2 (one or more areas of thick calcification), and grade 3 (circular calcification of the aortic knob) [ 20].
In order to quantify cell shedding and local barrier dysfunction at CLE we developed a grade based on the human and animal experiments described above and validated the grade by its prediction of subsequent relapse of CD and UC (table 1).
