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Therefore, new enediynes would be extremely valuable assets in the development of safer, more effective ADCs with a validated mode of action.
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Furthermore, in keeps in place what is essentially a denial of academic freedom, as minority scholars feel they must stick close to a conservative, validated mode of research and teaching.
We thus thought to evaluate tamoxifen in Mtm1−/y mice, a validated model of XLMTM15,38,39,40.
A validated experimental approach to obtaining critical mode I and mode II energy release rates for interfacial failure in a sandwich composite panel is outlined in this paper.
An extensive numerical experiment are conducted considering a 1.6 L single cylinder engine with a reentrant piston bowl running in HCCI mode employing a validated ECFM-3Z (Extended Coherent Flame Model-3 Zones) (STAR-CD) combustion model.
Common carotid artery intima-media thickness (CIMT), measured by B-mode ultrasound, is a validated surrogate measure of preclinical atherosclerosis and was shown to be a predictor of future cardiovascular events [ 4].
The Sexual Modes Questionnaire (SMQ) is a validated and widespread used tool to assess the association among negative automatic thoughts, emotions, and sexual response during sexual activity in men and women.
Time intervals of emergency care, source of referral, medical problems, diagnostic procedures, and mode of discharge after ED treatment were assessed by a validated outcome tool ("emerge") [ 8].
Using a validated therapeutic epigenetic protein, we evaluated fluorinated bromodomains as sensitive tools for detecting ligand binding modes via F NMR.
A validated, semi-structured questionnaire was administered in face-to-face interviews to collect data on demographics and mode of breast cancer detection.
A validated algorithm (National Cancer Intelligence Network, 2013) was applied to Hospital Episode Statistics HESS) patient care data to identify new cancer cases and their mode of presentation and then to calculate the percentage of HES-identified cancers first presenting as an emergency.
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