The purposes of this study are (a) to describe the process of recording the cause of death in the Geneva Cancer Registry, (b) to investigate how accurate the routinely recorded cause of death is compared to the validated cause of death derived from clerical review and (c) to examine whether the process of validation leads to differences in the estimates of cause-specific survival.
These physiological changes are especially relevant as de novo or inherited mutations in PTEN are emerging as one of the most validated causes of autism spectrum disorder, intellectual disability and extreme macrocephaly.
For instance, 6-TX and FUDR are nucleotide analogs that could result in mutations in the genome, whereas phleomycin is a validated mutagen in Toxoplasma, causing double-strand breaks [ 63].
It is a validated questionnaire to assess the most probable cause of cough.
Briefly, we adapted a validated verbal autopsy procedure to ascertain the causes of death in cohort participants (Chen et al. 2011a).
Deaths were recorded through an active reporting system and probable cause of death determined by a validated verbal autopsy [ 15, 16].
One limitation of this study is that we did not use a validated verbal autopsy technique when obtaining information on cause of death as this was not a principal objective, and therefore these results should be interpreted with caution.
Clinically, the intima-media thickness (IMT) is used as a validated measure for the assessment of atherosclerosis, that causes enlargement of the arteries and thickening of the artery walls.
SPARC is a validated screening tool used to identify distressing symptoms caused by an advanced illness [ 22].
Mortality and cause of death were ascertained with a validated program, the California Automated Mortality Linkage System.
The lack of a validated tool, which reliably assesses changes in cognitive performance caused by RF EMF exposure, may contribute to the current inconsistencies in outcomes.
