Often, herd immunity is not shown when health authorities recommend a vaccine and implement a vaccination program under systematic surveillance.
We investigated, in the context of the emergence of a vaccine-resistant strain, whether a vaccination program can prevent the spread of infectious disease.
We designed and analyzed a deterministic compartment model illustrating transmission of vaccine-sensitive and vaccine-resistant strains during a vaccination program.
With a vaccination program, some children may not be vaccinated, and because vaccine efficacy is less than 100% against rotavirus diarrhoea, some vaccinated children also will become ill.
Herein, we describe a homogeneous population model of infectious disease and its control using a vaccination program in the presence of a vaccine-resistant strain (Fig. 1).
A vaccination program would be justifiable should a vaccine become available.
We extended the standard susceptible infective model [30] including the effect of a vaccination program that can engender the emergence of a vaccine-resistant strain.
The closest county with a vaccination program was ≈80 km away and vaccinated only students (29,000 doses in 2001).
If more than half of the cows must be vaccinated to achieve effect, the initial costs for introduction of a vaccination program increases.
The economic model was based on the difference between the costs sustained with (vaccine plus treatment for expected cases) and without (only expected cases) a vaccination program.
Others say we can help more people by contributing to a vaccination program in developing countries.
