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This is largely a useless question, so I will provide a useless answer.
Obviously, the extreme case of defining each single pair of atoms as a separate cluster would lead to minimum STDDV within clusters but would represent a trivial and useless solution.
The application of the Axiomatic Design has a key role in defining the software architecture, avoiding useless solutions and improving code optimization from the earliest phases.
Failing to identify its source may lead to temporary and useless solutions.
The most common approach is to lower the solubility of its component molecules very gradually; if this is done too quickly, the molecules will precipitate from solution, forming a useless dust or amorphous gel on the bottom of the container.
That was a useless article.
Like a useless gimp.
"You're a useless leader.
A useless question, probably.
He's a useless speaker.
I am a useless mother.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com