Reactome is a major, useful pathway resource, which includes peer-reviewed, manually curated human pathways and electronically inferred pathways in 22 non-human species using protein similarity.
We developed a set of useful pathway pruning and analysis criteria to systematically assess thousands of pathways generated by BNICE.ch.
Two rules are used to select the most useful pathways.
Therefore, Pathway Projector can serve as a useful gateway for pathway information analysis.
In organic synthesis, hydrothermal in situ ligand syntheses have become very useful pathways to organic ligands, which are difficult to obtain by routine synthetic methods.
The increased efficiency of catalysis carries over to resistance against side reactions [ 41] that constantly divert material from useful pathways.
Our data revealed not only interactions between genes that illustrate useful pathways for new therapeutic targets but also for understanding the mechanism of selectivity of CDV.
For application to disease, other resources such as BioCarta and the Pathway Interaction Database may be a useful source of pathways.
Michele Pritchard (Cleveland Clinic, OH, USA) identified the protective effects of adenosine signaling in ethanol-induced liver injury, which may be a useful anti-inflammatory pathway to target and to attenuate the pathophysiological effects of ethanol in the liver.
Gene set enrichment analysis (GSEA) proposed by Subramanian et al. [ 16] and extended by Hung et al. [ 19] to include network topology is a useful tool for pathway-based class distinction.
