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As a key precursor of coenzyme A (CoA) biosynthesis, pantothenic acid has proven to be a useful backbone to elaborate probes of this biosynthetic pathway, study CoA-utilizing systems, and design molecules with antimicrobial activity.
In conclusion, TMEM16A 0) may represent a useful backbone, suitable for structure activity relationship studies in which progressive additions of alternative segment regions will help in elucidating their functional roles.
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The existence of relatively well-sampled large-scale alignments provided a potentially useful backbone to analyse the taxonomic placement of the poorly known Ethiopian frog Ericabatrachus baleensis.
Weekly docetaxel-based chemotherapy provides a useful chemotherapy backbone for evaluation of targeted agents, and the AGITG is currently evaluating the efficacy and safety of adding the epidermal growth factor receptor-targeted antibody, panitumumab, to wTCF chemotherapy as treatment for this disease.
Thus, the α-C-glucosidic structure was shown to be a useful mimic of the myo-inositol backbone of IP3.
Manipulating conformational flexibility of the carbohydrate backbone of Lipid A represents therefore a useful tool for the rational design of potential MD-2/TLR4 specific MD-2/TLR4 specifictherapeutics.
The synthesis may provide a useful route to extended π-conjugated systems having central pyrazine moieties in their backbone.
Anyway, a useful lesson.
This is a useful move".
And a useful one.
A useful innovation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com