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The phrase "a unique situation in" is correct and usable in written English.
It can be used to describe a specific circumstance that is distinct or different from others in a particular context.
Example: "This is a unique situation in which we must consider all possible outcomes before making a decision."
Alternatives: "an exceptional case in" or "a distinctive scenario in".
Exact(24)
"This is a unique situation in Argentina.
"I.B.M. had a unique situation in essentially having a product that no one else had," Mr. Hoagland said.
"Number one, you need to realise this is a unique situation in order to do something about it; number two, you have to set up the machinery which is not subversive of the overall negotiations," he added.
"You must realize, as I know you do, Florida is in a unique situation in the context of this event," said Tim Moore, commissioner of the Florida Department of Law Enforcement.
If the government has indeed convinced the company to keep the price of the Big Mac down, while allowing others to rise, it would hardly be a unique situation in a country where price agreements have become common.
Microreactors employing thin catalytic films present a unique situation in catalyst design owing to the removal of symmetric internal boundary condition (i.e. zero heat flux) employed in catalyst design analysis to-date.
Similar(36)
A unique situation prevails in PHC services, namely that they reach practically the whole community on a one-to-one basis.
This is a unique situation, because in all subsequent rounds of mitotic PCM recruitment, the centrioles are already associated with at least a small amount of PCM that was present on the centriole during interphase.
"Although the critical mass of construction projects taking place in Lower Manhattan makes it a unique situation," she said in a statement, "the city would welcome involving artists in other areas around the city that are undergoing major transformations".
Mukugodo are in a unique situation among Kenyan pastoralists, in that they live in a region surrounded by large-scale private cattle ranches that also engage in wildlife conservation and tourism, forcing them to compete and/or engage in risky negotiations with more powerful individuals for access to land.
"We've always been a generous nation taking in refugees, but this is a unique situation," Ryan said in an interview with talk-radio host William J. Bennett.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com