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The phrase "a unique requirement of" is correct and usable in written English.
It can be used when specifying a particular need or condition that is distinct or one-of-a-kind in a given context.
Example: "The project has a unique requirement of advanced technical skills that not all team members possess."
Alternatives: "a specific need for" or "a distinct condition of".
Exact(3)
A unique requirement of underwater vehicles' power/energy systems is that they remain neutrally buoyant over the course of a mission.
In the past 3 years, several reports have shown Klf5 to be an important player regulating ESC self-renewal, pluripotency and embryonic development with a unique requirement of Klf5 in inner cell mass (ICM) establishment compared to the other ESC-specific Klfs [ 16, 17, 30- 32].
Piccinini and Midwood now show a unique requirement of the extracellular matrix protein tenascin-C in macrophages at the forefront of bacterial invasion, where it is needed to drive production of microRNA miR-155, which enables sustained expression of proinflammatory cytokines such as TNF-α.
Similar(57)
Taken together, these data suggest that ATRX-bound intragenic CGIs, including imprinted DMRs, have a unique requirement for ATRX-mediated deposition of H3.3 and that these interactions are necessary for the maintenance of H3K9me3 at these sites.
The DN mutant results might be interpreted as suggesting that there is a unique requirement for Btl activity for generation of GB cysts.
Another unique requirement of datacom systems is distance.
Development of a cell-based functional assay for large-conductance calcium-activated potassium (BKCa) channels is challenging because of the unique requirement of both voltage and high concentrations of Ca2+ for activation of these channels.
The proposed PD rehabilitation design framework employed for the games pilot testing utilises a low-cost, customized and off-the-shelf motion capture system (employing commercial game controllers) developed to cater for the unique requirement of the physical therapy of people with PD.
Although NR286 T cell regulatory function was dependent on cell-contact with target cells, their unique requirement of IFN−γ and NO for their regulatory functions and the fact that they did not express Foxp3 distinguishes them from Foxp3-expressing nTreg.
This can explain the unique requirement of Klf5 for derivation of ESCs and ICM proper development [ 17], in contrast to the dispensable role of Klf2 and Klf4 in these processes [ 31, 32].
The objective of this study was to investigate whether the previously reported differences in the equilibrium between the closed and open monomer arrangements, KCO, was caused by differences in helical stability and whether the differences in KCO might contribute to the unique requirement of TGF-β1 and TGF-β3 in vivo that has been previously suggested based on gene replacement and other studies.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com