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FAK serves as a unique regulator of FA assembly and disassembly, processes that are fundamental for efficient directional cell movement8,9.
dhCer serves as a unique regulator of cell fate, controlling the 'switch' between cytoprotective autophagy and Cer-mediated apoptosis in response to stress.
Multiple lines of evidence indicate that nuclear-localized PHB protein is a unique regulator of specific transcription factors and cell cycle-associated proteins.
It is likely to be a proliferation marker rather than a unique regulator of cell proliferation and survival in stem and cancer cells.
Collectively, NS expression widely occurs in normal and malignant renal tissues, and is likely a proliferation marker rather than a unique regulator of cell proliferation and survival in stem and cancer cells.
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A rare sugar, d-psicose has progressively been evaluated as a unique metabolic regulator of glucose and lipid metabolism, and thus represents a promising compound for the treatment of type 2 diabetes mellitus (T2DM).
Spx is a member of the ArsC (arsenate reductase) family of proteins and is a unique transcriptional regulator of Gram-positive bacteria [1].
DevR is a unique response regulator that employs a dual activation mechanism including relief of inhibition and cooperative interaction with binding sites.
S1P recently has been characterized as a unique bimodal regulator of cell migration in the thymus and lymphatic system [27], an important determinant of plasma cell homing from lymph nodes to BM [28], and a key regulator of the physiologic recirculation of HSC and progenitor cells [29].
© 2012 Wiley Periodicals, Inc. Retinoic acid (RA) is a unique lipid regulator of neural progenitor proliferation and differentiation.
Collectively, the present investigation identifies a HECT class E3 ubiquitin ligase Itch as a unique negative regulator of RASSF5, and suggests the possibility that acetylation as a potential therapeutic target for human cancer.
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