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Within one ionization mode, both corresponding parameter sets were each optimized for a unique latent molecular class.
The latent survivor time approach assumes conditional independence for the competing risks and a unique latent exit time for each of them.
The geographical distribution of the risk of the PPH conditions is captured in a 36% by a unique latent pattern.
The high membership probability observed even for patients with a low number of CD4 measurements allows us to assign patients to a unique latent trajectory with confidence.
(Modeling a unique latent variable requires at least two measurements of that variable, so to represent DBP and BzBP as distinct entities in the SEM would have required additional measures of DBP and BzBP metabolites).
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First, for each k-function with a fragmented genotype set, we calculated the number of unique latent phenotypes found in the dominant genotype network, but not in the peripheral genotype networks (i.e., those different from the dominant genotype network).
Specifically, we considered all of the circuits with a given monofunction and calculated the size of their latent repertoire, i.e., the number of unique latent phenotypes that these circuits collectively harbor.
Second, we calculated the number of unique latent phenotypes that were present in the peripheral genotype networks, but not in the dominant genotype network.
Finally, we found that the number of unique latent phenotypes per genotype network increased with the size of the genotype network (Additional file 1: Figure S10), similar to the association observed between latent repertoire size and genotype set size.
We calculated the fraction δ of unique latent phenotypes between two circuits as (3) δ = 1 - | e 1 ∩ e 2 | | e 1 ∪ e 2 |, where e1 and e2 are the sets of latent phenotypes of the two circuits in the pair [ 83].
EBV exhibits tumorigenic potential due to a unique set of latent genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com