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The phrase "a unique effect of" is correct and usable in written English.
It can be used when discussing a specific and distinctive impact or influence that something has on another thing.
Example: "The study revealed a unique effect of the new drug on patient recovery times."
Alternatives: "a distinct impact of" or "a singular influence of".
Exact(13)
Cold acclimation under L/D at 4°C, similarly to L/L at 4°C, caused valine levels to increase without corresponding changes in leucine or isoleucine, again pointing to a unique effect of cold on valine metabolism.
Although the great number of functions in which this protein could be involved make it difficult to rule out a unique effect of the observed VCP increase in AQP4−/− muscle, the protein-protein interaction map seems to suggest a particular role of VCP over-expression in the up-modulation of protein-ubiquitination homeostasis.
However, a unique effect of activation of the P2X7 receptor is formation of pores in the plasma membrane [ 12].
However, there is still no direct evidence for a unique effect of NDPK5 on ethanol levels in C. thermocellum.
Recent randomized control trials have failed to show a unique effect of CISD on posttraumatic symptoms, anxiety, or depression [ 9, 10] in high-risk occupations.
A unique effect of haloperidol is a relatively strong suppression of spontaneous musculoskeletal hyperactivity and behavior that results from hyperdopaminergic brain function, without pronounced sedation or hypotension.
Similar(47)
In a previous study of our group, frailty indicators indeed had an unique effect on institutionalization of older people after taking into account chronic diseases and disability [ 34].
Such a contribution was merely "one of the legacies of ancient Greece which have helped form western thought, society and art -- the product of a civilization which... had a unique effect on the history of mankind".
Over all services, we did not find a significant, unique effect of the forest attributes on ecosystem service correlations (Supplementary Table 4a).
In this case, we have experience of a unique effect: the universe.
Our results point to a relatively large unique effect of local and landscape scale variables at the community level, but we also show that results vary greatly depending on the trophic guild being analysed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com