From a medical point of view, especially the individual combination of nsSNPs may play a unique and crucial role in clinical diagnostics, in particular, within the context of complex genetic disorders.
Elegant studies based on electron microscopy have revealed that this feature of CBX2 has mediated a highly positively charged region located in its C-terminus not found in any other PcG member, thus suggesting a unique and crucial function for CBX2 in PcG-mediated repression.
The telomerase inhibitor griseorhodin A is probably the most heavily oxidized bacterial polyketide known and features a unique epoxyspiroketal moiety crucial for its activity.
The main difficulties for such a segmentation using a unique detection protocol, crucial for comparative studies, are: a. the cell shape variability between cells in each drop potentially depends on toxic compound concentration; b.
The completeness of the measurements on each satellite and the constellation aspect, however, implies simultaneous observations of a unique set of important electrodynamical parameters crucial for the understanding of the physical processes in Geospace, which are an important part of the objectives of the International Living With a Star Programme, ILWS.
In this scenario the need to collect information about genes and proteins in a unique resource becomes a crucial problem, despite the fact that several resources on biological pathways, like KEGG (Kyoto Encyclopedia of Genes and Genomes) Pathway Database [ 1] and Reactome [ 2], are already available for different organisms.
This is a unique opportunity to validate many crucial issues of the cryogenic part of such a sensitive instrument.
Osteopontin (OPN) is a unique acidic macromolecule with the crucial biological function of inhibiting urinary crystallization by possibly reducing the growth and aggregation of calcium oxalate (CaOX) crystals and inhibiting the binding of CaOX crystals directly to renal tubular epithelial cells [ 6, 7].
Though some of its woes are unique, a crucial one is not.
His place within the management of the sport, where he has been crucial since 1978, puts him in a unique position, he argued.
