Each cell in a SARM represents a unique compound, i.e., a unique combination of a key and value fragment.
These data indicate that MPH, a drug commonly used in the clinic, is a unique compound that has characteristics of both blockers and releasers and its effects at the DAT can be affected purely by variability in DAT levels.
The Z score for metHb (Zmet) was also calculated according to eq 2. 2 In this equation, metHb%cpd is the metHb% of hemoglobin incubated with a unique compound, and metHb%ctrl is the metHb% of hemoglobin without any added compound.
This resulted in an unprecedented effort to measure and publish bioactivity data, and the development of a unique compound collection, known as the Molecular Libraries Small Molecule Repository (MLSMR).
These properties include prozyme regulation of AdoMetDC (S-adenosylmethionine decarboxylase) activity in trypanosomatids, co-expression of ODC (ornithine decarboxylase) and AdoMetDC activities in a single protein in plasmodia, and formation of trypanothione, a unique compound linking polyamine and thiol metabolism in trypanosomatids.
But the dramatically increase of unique compounds of one order of magnitude from less than 10 to around 30 to 40 million compounds currently and approximately hundred million compounds in the next years requires a reorganization and redevelopment of the storage and searching strategy.
As Andrew Lambert states in his biography, Franklin: Tragic Hero of Polar Navigation, the story is "a unique, unquiet compound of mystery, horror and magic".
The story is "a unique, unquiet compound of mystery, horror and magic", as Franklin's biographer Andrew Lambert puts it.
The p-KG03 polysaccharide is unique compound with the molecular weight of 1.87 × 10, categorized as a homopolysaccharide of galactose conjugated with uronic acid and sulfate groups.
Phase I of ToxCast employed a chemical library of 300 unique compounds, most of which were chemicals for agricultural use, such as pesticides, and had relevant animal toxicity testing results available.
Marine ecosystem forms an important source of unique compounds with high structural uniqueness and incomparable chemical properties.
