If the uplifted surface had originally been low and without prominent relief, it is likely to remain relatively flat when uplifted to a relatively uniform elevation.
When cells are stimulated by flash photolysis of caged Ca2+, creating a uniform Ca2+ elevation, the earliest LB fusion events occur several seconds after the [Ca2+]c rise [13].
Both the range and the plateau are extensively dissected and of uniform elevation throughout, the highest point being reached at Victoria Peak (3,680 feet [1,122 m]) in the transverse Cockscomb Range, which extends seaward perpendicularly from the main divide.
The eastern part of the Plateau of Tibet, which constitutes the headwaters of many of the great rivers of Asia (e.g., Huang He, Yangtze, Mekong, Salween, and Irrawaddy), is dissected into deep canyons separated by narrow, steep ridges; the high uniform elevation that characterizes plateaus is only barely discernible in that area.
The organic compounds in the matrices were burnt out under the conditions of slow and uniform elevation of temperature and big flow of oxygen gas in the stack.
However, progestin doses selected for use in current oral contraceptives are essentially equipotent (Collins, 1994), perhaps explaining the fairly uniform elevation in breast cancer risk across progestin types seen in this study.
For example, in the calyx of Held, a giant synapse in the brainstem, it was shown that SVs involved in the slow phase of evoked release triggered by prolonged depolarization are as sensitive to Ca2+ as those in the fast phase, and can undergo rapid release upon uniform elevation of intracellular Ca2+ (Wadel et al., 2007).
The second messenger concept, as proposed many decades ago, originally portrayed global, uniform elevations of Ca2+ and cAMP as simple on/off switches for controlling cell function.
