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The phrase "a two fold increase" is not correct in standard written English; it should be "a twofold increase." You can use it when describing a situation where something has doubled in quantity or value.
Example: "The company's profits experienced a twofold increase this quarter compared to the last."
Alternatives: "a doubling" or "a two times increase."
Exact(7)
Aggregation of CUG RNAs within the cytoplasm results both in Mbnl1 sequestration and in approximately a two fold increase in both nuclear and cytoplasmic Cug-bp1 levels.
The blend hydrogel scaffold showed a two fold increase in cell number over control within three days of culture.
In untreated NHEKs, calcium stimulation resulted in a two fold increase in involucrin mRNA levels.
There was a two fold increase in glioblastoma cell death following TQ treatment compared to untreated controls.
Drug exposure in general was associated with a two fold increase risk of stillbirth [ 8].
ovol1 has a two fold increase in expression in males than in females in later stages in development.
Similar(53)
As early as four hours we could detect a two-fold increase in CYLD protein levels (Figure 4D).
A two-fold increase was found for the three parameters using 100 particles per cell.
We hoped for a two-fold increase in visitors, but immediately there were four times as many.
Not all of them involved domestic workers, she said, but that number represents a two-fold increase in such prosecutions compared with the seven years before 2000.
Not a two-fold increase but a 20-fold increase in the amount of content a local publisher exploits".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com