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Discover LudwigThe phrase "a two fold change" is not correct in standard written English; it should be "a twofold change." You can use it when describing a change that has two distinct aspects or components.
Example: "The new policy resulted in a twofold change in employee productivity and morale."
Alternatives: "a dual change" or "a two-part change."
Exact(1)
Two genes, Rv2631 and Rv0571c, were excluded by STEM prior to clustering as the expression changes were smaller than the default threshold of one unit (that is, a two fold change in expression levels) in STEM.
Similar(59)
Only 174 probesets showed an increased signal, including nine with a two-fold change.
To facilitate further analysis, we filtered for genes exhibiting at least a two-fold change in expression in two consecutive time points, which were considered as significantly regulated.
Two filtering criteria were used to define differentially expressed genes (DEGs) in our data analysis: a two-fold change in transcript levels among every two time points and a P value ≤ 0.05.
The matrix contains three groups of genes: those displaying a two-fold change in expression under both conditions, and those displaying a two-fold change in expression under either condition but not for the other.
More than half of the differentially expressed genes showed at least a two-fold change in expression level in all three pairwise comparisons (Table 3).
In the first synthetic dataset, each gene had a two-fold change corresponding to the log-ratio changing by unity between the time point 5 and 6.
Each germination condition was handled independently and two cluster analyses were performed: (i) clustering of genes displaying a two-fold change in expression level following addition of that particular germinant (ii) clustering of genes displaying a two-fold change in expression level in the second germinant.
We found that for experiment one, only 14.6% (21/144) target RNAs show greater than a two-fold change (increased or decreased) in abundance when LARK is overexpressed.
To validate the microarray results, qRT-PCR was performed with seven miRNAs that exhibited a > two-fold change in expression (Table 2).
The MA plot indicates 3857 DB sites with at least a two-fold change and a FDR < 0.05, 2281 DB in NaBt-treated cells and 1548 in control cells (Fig. 7a).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com