Almost all natural TTR amyloid deposits, and in particular those involving the heart, contain a truncated form spanning residues 49 127 and the abundance of this fragment correlates with the severity of cardiac amyloidosis.
We used OP91H*, a truncated opsin mutant that spans the membrane twice (type I and type II oriented transmembrane domains) and can be bi-glycosylated in the N-terminal region [ 14].
The hypothetical protein harbors a 177 aa N-terminal nitrilase domain (pfam00795; involved in nitrile hydrolysis to ammonia and carboxyl acid) spanning aa positions 3 180, and a truncated 74 aa MULE domain spanning aa positions 363 436.
The nanodegree offered by Udacity is its own original form of accreditation, which is based on a truncated field of study that spans months, rather than years, and allows students to direct the pace of their own learning.
Based on this analysis we defined a truncated form of B. subtilis FtsZ spanning residues Ala12-Ile316 (termed "FtsZ truncated").
A truncated form lacking the flexible loop spanning amino acids 27 82 and the last 24 amino acids, which are the transmembrane domain, was inserted into the pET15b vector which introduces an N-terminal histidine tag and a thrombin digestion sequence.
We disentangled the motor and attention functions using statistical analysis with subspaces spanned by vectors generated by a truncated trigonometric series of motor and attention frequency.
A truncated version of ZFD was also prepared, which spans residues 259 338, with the last 20 flexible residues removed.
For example, a cryptic splicing junction-spanning read will show that the mRNA contains a truncated or extended exon at the predicted location, which is directly attached to the sequence of the corresponding adjacent exon.
Two mRNAs are reported for this gene: isoform 1 (NM_153840.2), which encodes the full-length protein containing the characteristic seven-span transmembrane region of G-protein-coupled receptors, and isoform 2 (NM_025048.2), a truncated version of isoform 1.
MerFt, a truncated construct of the bacterial mercury transport protein MerF, was found to consist of two membrane-spanning α-helices and a short loop region.
