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Ptolemy's principal innovation in orbital astronomy — the so-called bi-section of eccentricity — entailed that half of the observed first inequality in the motion of the planets arises from a true variation in speed, and half from an only apparent variation associated with the observer being off center.
These data indicate that the changes in RGC dendritic segregation induced by EE reflect a true variation in RGC circuitry rather than alterations in retinal architecture.
Therefore, altered DRBP76 isoform expression in GBM is a true variation from the non-malignant state and does not represent a glia-specific phenomenon.
Given the relative completeness of the Cryptosporidium spp. genomes, the relative small number of E2 identified in C. hominis and C.parvum, eight and eleven, respectively, may suggest that these represent a true variation from the mean of 13 to 14 E2s found in Plasmodium spp. and T. gondii.
Moreover, no differences were detected in the number and morphology of retinal microglial cells between EC and SC pups (Fig. 1C), indicating that the changes in the pyknotic cell number induced by maternal EE reflected a true variation in cell death rate, rather than a change in the speed of pyknotic debris' clearance.
None of these NC calls corresponded to a true variation.
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Note that this normalization, while necessary to correct for clone-to-clone differences in measured ratios due to differences in GC content, excludes an ability to detect any true variation in methylation levels that might correlate with GC content.
There may also be seasonal fluctuation in length of seals [ 12], though the cross-sectional nature of the study cannot distinguish between a true fluctuation or simply variation between cohorts.
Effect sizes may differ under this model, not only because of random error within studies (as in the fixed effects model), but also as a result of true variation in effect sizes between studies.
The way AGEP works is that we assume that the whole spectrum of expression values for a gene in a tissue reflects the true variation in vivo.
This provides the reader with the true variation, as a supplement to the ICC.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com