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CDC epidemiologists and toxicologists reviewed these data daily using set criteria to determine if a true exposure had occurred.
While the latter two are determined (with a certain measurement error) by the true exposure (η1), it may seem more natural to consider pilot whale meat intake as a determinant of a true exposure: an increase in maternal whale meat intake will increase the mercury exposure, not the other way around.
Local and national events that involve a potential rabies case may affect how persons and physicians assess the risk of an animal exposure, perhaps leading to use of PEP in an environment of heightened concern rather than in response to a true exposure (21, 22 ).
Further research is needed to determine the lowest infectious dose, define what constitutes a true exposure for which antibiotic prophylaxis is warranted (especially in light of possible drug side effects), and determine whether spores delivered in an envelope create a residual risk after the primary contamination event.
Without individual-level data on specific chemical exposures and competing risk factors over long latency periods, the few associations seen to date are more likely due to multiple comparisons and presence of competing risk factors than to the unmasking of a true exposure effect.
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The estimated variance ratio is a measure of the attenuation bias (smaller is better) when using a surrogate for true exposure (albumin adduct levels in this context) to predict an exposure disease relationship (Lin et al. 2005).
Alternatively, dust in the family room is necessarily a surrogate for "true" exposure, either from bedding or via an airborne route.
Self-reported passive smoke exposure is only a proxy for true exposure levels, but is accepted as the most practical method of assessment.
Also, self-reported exposure is only a proxy for true exposure levels but is accepted as the most practical method of assessment.
It is still unclear if and to what extent the observed extremely high infection levels in Northern Senegal were due to intense exposure, and in how far the endemic-like age-related infection patterns were due to differences in exposure levels, measured by human water contact patterns as a proxy for true exposure.
In such a situation the true exposure R D t) may be calculated integrating out the covariate X: (4) ∫ − ∞ ∞ (S (t | Z = 1, X ) f (X | Z = 1 ) − S (t | Z = 0, X ) f (X | Z = 0 ) ) dx Pointwise confidence intervals for the CGPM are calculated using percentile bootstrap (200 bootstrap samples for each simulated data set).
Related(20)
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Justyna Jupowicz-Kozak
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