The shortage of medical supplies and equipment posed a challenge for those in charge of medical care, with the lack of soap and disinfectant being a particularly troublesome concern.
While investigators designing clinical trials face the important issue of endpoint selection, an equally troublesome concern can be the a priori selection of the endpoint analysis.
"It preserves a troublesome business model," she said.
The case of Massachusetts's Anthony Powell, wrongfully convicted and exonerated because of DNA tests, reflects a troublesome national concern: When the wrong people are convicted of heinous crimes, the guilty are free to reoffend.
This research also revealed a troublesome pattern concerning male undergraduates' strong aversion to certain styles (e.g., gangster, gay).
A problem that remained troublesome concerns the fact that one often wants to assign probabilities to particular events, events that in the nature of things cannot be repeated in all their particularity.
But marginalizing the episode -- a 42-year-old truck driver was charged with manslaughter after the other man died of brain injuries outside a hockey rink where their sons had played a pickup game -- is just a convenient way to deflect troublesome concerns before they creep too close.
p-value < 0.05 (significant in bold) As chronic child's disease may have an impact on the entire family functioning - parents of children representing common chronic diseases in childhood were invited to participate in a qualitative study to identify their most troublesome concerns.
Most troublesome concerns for parents of child with chronic disease included emotional distress and feeling depressed due to child's disease, avoiding social interactions due to child's disease or symptoms.
Britishness, in short, is a troublesome concept.
Strong axillary malodour in humans is generally perceived as socially offensive in most cultures and is a troublesome problem for the individuals concerned.
