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The phrase "a trial in itself" is correct and usable in written English.
It can be used to describe something that is challenging or difficult on its own, independent of any other factors.
Example: "The process of moving to a new city can be a trial in itself, requiring careful planning and adjustment."
Alternatives: "a challenge on its own" or "a test in its own right."
Exact(1)
The Princeton Junction station is a trial in itself.
Similar(57)
These studies require informed consent but not to the same commitment as for a trial which in itself might lead to more acceptable response rates.
The verdict followed a trial in June.
He is awaiting a trial in January.
A trial in 2012 ended in a deadlocked jury.
Additionally, there is always the risk that being in a trial will itself change the behaviour of healthcare professionals (the Hawthorne effect).
"While no single remark was so outrageous as to warrant a new trial in and of itself," the appeals judges wrote, "the cumulative effect of the People's summation deprived defendant of a fair trial".
Probably more criticized than praised, the trial is in itself a real achievement, as Mr. Maguire wrote in this newspaper in 2011, at the beginning of the current trial of Mr. Nuon Chea and his co-defendants, leng Sary, the former foreign minister, and Khieu Samphan, the former head of state.
(A trial ended in acquittal).
A trial resumes in early May.
A trial attorney in Chicago.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com