The standard for competence to stand trial, formulated in a 1960 Supreme Court decision, Dusky v. United States, is fairly basic.
The objective of the present study was a trial to formulate diclofenac sodium as controlled release microparticles that might be administered once or twice daily.
We used a trial design formulating C-82 for topical application and conducting a placebo-controlled, double-blinded clinical trial in which patients with diffuse cutaneous SSc were treated with C-82 or placebo on opposite forearms.
The amount of SOP used in this experiment was chosen with the criterion of practicality under farm conditions (the diets used in this trial were formulated on the basis of previous in vivo trials with Chianina bulls and dairy Comisana sheep; data unpublished).
We propose using data from a previous trial to formulate assumptions that can be used to simulate trials and thus improve the design of new trials.
The content used in the current trial was formulated by the research group, and we did not undertake a pilot study to explore responses to the wording of the e-mails.
This report summarises the scientific reviews and discussions as well as the recommendations regarding phase I trial design formulated by the MDICT task force.
Trial designs formulated by the latter are unable to mimic the boundaries of the unified family, which includes the two-sided symmetric designs of Emerson and Fleming, the two-sided designs of Pampallona and Tsiatis, and the double triangular designs of Whitehead and Stratton.
The present trial was formulated to evaluate the impact of megestrol acetate on quality of life, toxicity, response, and survival in individuals with extensive-stage small-cell lung cancer who received concomitant chemotherapy.
Criteria for exclusion and inclusion of trials were formulated in a study protocol in advance.
During the trial, cows were fed a diet formulated for late gestation (14.6% CP, 42.3% NDF, 20.5% starch, 7.1% ash, and 0.97% Ca) supplemented with Animate (Prince Agri Products Inc., Quincy, IL), with a resulting DCAD (Na + K − Cl − S) of −21.02 mEq/100 g of DM.
