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In all three subpopulations we observed only marginal (5%) increases in C > T (G > A) transitions (Additional file 1: Figure S4).
I passed a bill, after long negotiations with the mayor, long negotiations with the unions, to say, let's put another 7,500 people on, 2,500 people per year over the next three years, in a transitions jobs bill.
Two mutations were found in codon 13; both were G to A transitions, GGC to GAC (Fig. 5D).
Both are missense mutations that, remarkably, are due to G to A transitions of the same nucleotide resulting in cysteine to tyrosine substitutions.
Among four mutations in codon 12, three were G to A transitions, GGT to GAT; and one was G to T transversion, GGT to GTT (Fig. 5C).
Three of the four P. olsoni-specific substitutions correspond to either C to T or G to A transitions, which are commonly associated to DNA damage [44].
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Thus, approximately 12 G-to-A transitions should have been recovered in these PERV DNA analyses (nearly 90 if multiply recovered sequences would have been considered).
This damage included both fragmentation bias and elevated 5′ C-T/3′ G-A transitions near sequence ends.
Mutations on both strands were counted on the assumption that G-to-A transitions on the sequenced strand represent C-to-T transitions on the complementary strand.
The remaining three alleles s126, s1409, and s1519 are G-A transitions that introduce stop codons (W1011 Opal, W1492 Amber, W384 Amber respectively Fig. 1c).
Both of these involve inter-professional teams of medical and pharmacy students in the context of a transitions-in-care course.
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CEO of Professional Science Editing for Scientists @ prosciediting.com