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We allow activation of the switch only after a predefined number of consecutive predictions of a transition event in order to prevent premature activation of the switch and undertake a sensitivity analysis regarding the optimal choice of the (time) lag parameter.
Any method for change-point detection, in this case applied to cryptic transcription, will have greater power to identify a transition event that is flanked on either side by a large number of microarray probes.
For example, for any two time points T1≤T2 the probability of a transition event within the interval (T1, T2) is (P(T<T2)−P(T<T1))/(1−P(T<T1)), where the probabilities are derived from the distribution function of T estimated by the parametric survival model (eqn 2).
An important example of a transition event is when a person moves from hospital into an aged care facility.
Here the renewal process is again associated with a cooperative behavior, but the emergence of the self-organized structure is not associated with a transition event dynamically connecting one meta-stable structure to another.
The transient upregulation of GAP43 apparently represents a transition event during the acquisition of a neuronal-like phenotype and a type I diabetic environment attenuated the neurogenic response of cardiac nestin cells to ischemia and 6-hydroxydopamine.
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1 In particular, postmenarchal and premenopausal women may develop oestrogen-dependent diseases such as endometriosis and uterine myoma. 2 While some diseases decline in frequency after menopause, others, such as hyperlipidaemia, occur more frequently, demonstrating that menopause represents a major transition event in a woman's life course.
The codons of these two amino acids are also easily convertible to each other through a single transition event from T to C (GTN for V to GCN for A).
In alloys with higher rare-earth content, a glass transition event was clearly detected before the crystallization event.
Although we currently lack data from several Wolbachia supergroups, notably F, our analysis supports a model wherein the putatively mutualist endosymbiotic relationship between Wolbachia and nematodes originated from a single transition event.
The thermograms of the blends exhibit either a single glass transition event, characterized by a quite broad temperature range, or two glass transitions.
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