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Photoexcitation of SRI causes a transient shift in the equilibrium of the two conformations, and the behavioral response of the cell.
Although the Y197C,V266H mutant had a transient shift in helix 3, the E124A,Y197C double mutant had much more robust shift in the helix as compared with either V266H or Y197C,V266H.
Ganciclovir-induced apoptosis is accompanied by a transient shift in the dominant cleavage plane of mitotic cells in the dorsal pallial ventricular zone, which may contribute to the early replacement of GPT neuroblasts in ablated mice by the symmetric division of their non-GPT progenitors (Sanada and Tsai, 2005).
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This transient shift in the steady-state distribution of EGFR likely occurs because recycling from the RE to the PM continues after EGF stimulation, whereas endocytosis of ligand-bound receptors at the PM is delayed.
The exact mechanism for these transient shifts in neurotransmitter levels, however, is still largely unknown.
Activating KIRs appear to be especially short lived and recurrently evolving (45), implying that they are subject to transient shifts in selection pressure over time.
The polyneuropathy in patients without nerve degeneration has been proposed to be due to a transient negative shift in voltage dependence of sodium channel fast inactivation leading to reduced excitability of the nerve, demonstrated in both rats and humans [ 79].
The inset of part B of Figure 2 shows the traces offset to a common baseline, with transients shifted in time so that all decays go through 0.5 μA simultaneously.
The lateralized tactile cue stimuli induced a transient exogenous shift of attention, which was, however accompanied by an endogenous shift of attention only in the 75% and in the 25% cue validity conditions.
First, JNK phosphorylation, in response to ROS or ΔMEKK1 ER* activation, correlated with a transient mobility shift of PIAS1 on SDS-PAGE.
In the liquid condition, the identical regions instead showed a shift in transient activation from a reactive control pattern (primary probe-based activation) during no-incentive trials to proactive control (primary cue-based activation) during rewarded trials.
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