Features of the program included a transient reduction in global translational activity and a severe decrease in polysome size of transcripts encoding ribosomal proteins.
Consumption of foods results in a transient reduction in hedonic value that influences the extent and nature of feeding behavior.
Immunoblotting showed that ethanol induced a transient reduction in Rab6 after 5 days of ethanol exposure, whereas Rab3B decreased after 20 days, Rab11 after 30 days, and Rab1B after 60 days.
Acute tryptophan depletion (ATD) putatively results in a transient reduction in central serotonin transmission, and induces depressed mood in some un-medicated subjects with remitted major depressive disorder (MDD).
Although complete protection was not achieved at 5 weeks, a transient reduction in viremia (approximately 100-fold) occurred in the immunized macaques early after challenge compared to the nonimmunized controls.
Early treatment results in a transient reduction in the size and number of the GVF scotomas, but as the scotomas improve, there is no corresponding improvement in PR signal.
A transient reduction in epithelial monolayer integrity and epithelial fracture for ectocervical and colorectal explants was noted and likely due to the hyperosmolar nature of the formulation.
We used the tet-off system to test the hypothesis that a transient reduction in gene expression will sensitize a promoter to undergo epigenetic silencing.
Our work with tenofovir gel shows a transient reduction in the transepithelial resistance of the epithelial cells and fracture of the ectocervical and colorectal epithelium.
This is consistent with experimental data demonstrating that photoactivation of caged calcium in the cytoplasm of growing pollen tubes causes a transient reduction in the growth rate [47], [48].
This study demonstrates that a transient reduction in gene expression triggers a pathway for aberrant silencing in mammalian cells and identifies histone deacetylation as a critical early step in this process.
