The phrase "a topic of significant" is correct and usable in written English.
It can be used when discussing subjects that hold considerable importance or relevance in a particular context.
Example: "Climate change is a topic of significant concern for scientists and policymakers alike."
Alternatives: "a matter of considerable" or "an issue of great".
"Carter is worse," said one official, who spoke on condition of anonymity to discuss a topic of significant internal acrimony within the Obama administration.
Automated human emotion detection is a topic of significant interest in the field of computer vision.
Thus, biofilm formation by P. aeruginosa is a topic of significant medical importance.
Benefits At Stake The question of unemployment benefits is currently a topic of significant debate in Congress.
Such considerations have made the debate on optimal policy for various contexts a topic of significant discussion [20].
Based on these developments, research in the relatively new area of nano-energetics has become a topic of significant interest.
Time delay estimation has been a research topic of significant practical importance in many fields (radar, sonar, seismology, geophysics, ultrasonics, hands-free communications, etc).
While we recognize that restoration of habitats provides numerous benefits additional to CCS (e.g. nutrient cycling, coastal stabilization, preservation of biodiversity), we focus on CCS as a current topic of significant global concern and debate.
Although the function of punctae remains a topic of research, a significant result of their presence is the apparent increased exposure of the intercrystalline organic matrix to molecules in the surrounding medium.
This is a very complex topic of significant importance and interest not only to anesthesiologists, but also to parents and, of course, the patients.
if legislators decide that more DNA should be collected, Gascon said, "that is a topic worthy of significant debate".
