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Evaluations were made at 1 week, a timepoint of overuse when only mild inflammation and limited changes in the muscle structure are noted in animals not treated with inhibitors.
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Explore how clinical uncertainty and cognitive biases may lead to overuse—Uncertainty is inherent in medicine and is a driver of overuse.
However, GAG content is increased in this model as a function of overuse [ 13].
This is resulting in a virtual epidemic of overuse injuries.
"The fishery story is a sad case of overuse by humans," says Bongaarts.
This implies a high risk of overusing vasoconstrictor drugs and aggravating tissue hypoperfusion.
Poor result in Cooper's test was a warning signal of elevated risk of overuse injuries.
The number of reads for each mutant in a timepoint "i" was normalized for the sequencing depth of the same timepoint (reads per mutanti/depthi).
All studies analysed RCD in humans or the effects of overuse in an animal model.
There was no evidence of overuse of budesonide/formoterol as a reliever medication.
Research into the effects of overuse in medicine is uncoordinated More research is needed to define the extent of overuse and its harms Adoption of standard terminology is essential to better understanding Public agencies are needed to monitor overuse Evaluation of current efforts to curb overuse is also a priority Cite this as: BMJ 2015 351:h4534.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com