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At a time when alternative comedy was fashionable and the schedules were pebble-dashed with brilliant new shows such as Black Books, Human Remains and Marion and Geoff, My Family was producer Fred Barron's attempt to reintroduce a mainstream sitcom to UK schedules.
Cheez TV was sold to us as children as an alternative, in a time when alternative was not reflective of Australian society at large.
The following year, at a time when alternative rock and grunge was at its height, Tool released their first full-length album, Undertow (1993).
At a time when "alternative facts" are equated with reality, it is important for people of faith to again affirm their trust in a worldview that, building on the Enlightenment, prizes the scientific method.
In silico approaches offer the opportunity of improving the decision making at a time when alternative lead compounds are still in scope, and before considerable expense and time has been committed.
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Boards would agree to this exclusivity but in exchange demand a period of time when alternative bids could be solicited.
Today, because many clinical trials of new molecular-targeted agents for HCC are being conducted, it is necessary for hepatologists and oncologists to determine the time when alternative agents should be started as a second or third line of treatment.
And there was a time when the alternative minimum tax didn't exist.
"In a time when the alternative has been monetized we represent the constant push toward a nonhierarchical structure that finds its strength in solidarity and numbers," MINT says.
Nevertheless, enfuvirtide saved many lives when it came on the market at a time when no alternative new drugs were available.
Nevertheless, the failure is a high-profile blow both to the credibility of the agency (contradictory stories like this never look good) and its perceived reliability — critical at a time when private alternatives like SpaceX are gearing up to compete directly with Russia's lucrative launch business.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com