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As a result, a tighter interaction between PHY and MAC layers is achieved [14 16].
Dimerization has been used by this flavoenzyme in evolution to achieve maximal activity, a tighter interaction between the protein moiety and the coenzyme, and higher thermal stability.
It is expected that the elimination of the buffer resulted in a tighter interaction between the different components.
The observed increase in binding affinity is likely due to removal of potential alternative competing structures, thus allowing a tighter interaction between the protein and the RNA.
The relative ω values for Crm1 suggest a tighter interaction between the human Crm1 monomers, but the absolute value of ω > 1 for murine Crm1 still suggests some interaction between monomers.
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Hence, it might be relevant to determine whether OipA interaction with the host cell membrane mediates a tight interaction between H. pylori and host cells, allowing CagL to interact with β1 integrin, or whether OipA also targets β1 integrins directly.
Finally, the overlay paradigm allows for a tight interaction between primary and secondary systems.
It is therefore not surprising to find a tight interaction between hormone and light signalling pathways.
Firstly, we discuss a DNA hairpin assay where force-induced strand separation triggers a tight interaction between DNA-binding protein Tus and its binding site Ter, where forces up to 90 pN for hundreds of seconds were required to dissociate Tus from Ter.
We further assumed —based on evidence in favour of a tight interaction between the Notch and Wnt signalling pathways in mice [19]— that this gene and another subject to regulation by FGF and/or Wnt (W) interact by up-regulating each other's expression.
The underlying reason for the mandatory requirement for α-Syn in formation of p-Tau is not clear, but our studies suggest that α-Syn can recruit and activate GSK-3β, via autophosphorylation at Tyr216 [26] [27], suggesting a tight interaction between α-Syn and p-GSK-3β is necessary for Tau hyperphosphorylation.
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