The phrase "a tight interaction of" is correct and usable in written English.
It can be used to describe a close or strong relationship or connection between different elements or factors.
Example: "The success of the project relies on a tight interaction of various team members' skills and expertise."
Alternatives: "a close interaction of" or "a strong interaction of".
Additionally, this phenomenon can occur either because of a tight interaction of the SH2 domain with the kinase domain or from the conformational exchange between states.
Again, the significant amount of immobile KV10.1 and the restricted diffusion of the remaining mobile protein suggest to a tight interaction of KV10.1 with its INM environment.
TIM and many (but not all) such natural enzymes are most active as dimers, caused by a tight interaction of 32 residues of each subunit in the wild type, though functional monomers can be created.
In the DPAT series, however, Sahlholm et al. suggested that the rigidity of the ring system results in a tight interaction of the aromatic ring without the need for additional hydrogen bonding interactions.
This is because of a tight interaction of the oxo group with one of the protons of Arg210, which is shortened from 2.414 Å in R to 1.888 Å in TSI and then elongates again toward R′ to a value of 2.470 Å.
The decrease in the Km is the result of a tighter interaction of the prothrombinase complex with the membrane surface, which results in higher local concentrations of the enzyme, while the increase in the kcat of the enzyme is credited solely to the productive interaction between factor Va and factor Xa (3− 5).
Structural analyses of Akt1 bound to Akti1/2 revealed a tight interaction between Trp of Akt1 and the inhibitor [ 36] and mutation of Trp to alanine renders Akt1 insensitive to Akti1/2 [ 24].
From a genetic point of view, an autoimmune condition is the result of a tight interaction between environmental factors and specific predisposing genes.
We further assumed —based on evidence in favour of a tight interaction between the Notch and Wnt signalling pathways in mice [19]— that this gene and another subject to regulation by FGF and/or Wnt (W) interact by up-regulating each other's expression.
A picture of a tight interaction among genetic sex, sex steroid hormones, and the epigenome in shaping the dimorphic brain is now emerging.
This circumstance warrants a tight interaction between the different scientific and operational disciplines, which should enhance the mitigation of hazards.
