Additionally, we highlight a number of miRNAs whose tight developmental regulation may reflect a functional role in other stages of embryogenesis.
Drosophila haematopoiesis is thus an excellent model in which to study the tight developmental control of ROS levels that might play a key role in the transition from HSCs to myeloid progenitors in mammals (Tothova et al., 2007).
For example, it is these kinds of data that allow us to understand the tight developmental connection between the stemmata of holometabolous larval and adult eyes.
MECP2 expression is under tight developmental regulation, which is required for proper postnatal brain development.
Many of the GA oxidase genes are subjected to tight developmental [ 28, 29] and/or light (light quality, photoperiod) regulation [ 30- 32].
The genome-wide analyses indicate tight developmental regulation of genes functioning in diverse processes such as transcriptional regulation, sugar transport, lipid metabolism and cell wall rearrangements.
Research in the field has thus tended to be descriptive, since developmental psychology lacks a tight net of interlocking theoretical propositions that reliably permit satisfying explanations.
Gradients of two morphogens, decapentaplegic (Dpp), a member of the transforming growth factor- β family, and wingless (Wg), a member of the Wnt family, establish a tight link between cell proliferation and developmental programs.
Homeostatic meristem activity requires a tight control of stem cell proliferation with the developmental and nutritional status of the entire organism.
These analyses allowed determination of transcript levels for a large number of genes, helped to refine the original gene model and revealed a tight regulation of gene expression throughout the intraerythrocytic developmental cycle (IDC) of P. falciparum.
