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This suggests that there might exist a threshold in the severity of the acute disease, above which later virus control is impaired.
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This will help define a threshold for the severity of hepatic steatosis that can be correlated with adverse outcome.
However, when the percentage of mutant mtDNA exceeds a threshold in the range of 60% 95%, depending on the severity of the mutation, pathogenic mtDNA mutations can lead to various clinical manifestations (Russell and Turnbull, 2014).
Surprisingly, the enhancement of para bss1 by chn was limited to BS paralysis recovery time phenotype, that is, an increase in the severity of this phenotype; there was no apparent enhancement of the other major phenotype: threshold for evoked seizure.
Rather than apply a single threshold, there may be different (implicit) thresholds depending on the severity of the disease or an assessment of patient need [ 22].
The simplest explanation for differences in the severity of phenotype and pathology is a dose-threshold effect.
The percentage of deaths attributed to pneumonia and influenza rose slightly to exceed the epidemic threshold, a crucial determinant of the severity of an influenza season.
Furthermore, basing VAC surveillance upon increases in ventilator support sets a threshold effect for severity of complications: only patients with severe enough complications to merit a sustained increase in ventilator support are captured by this definition.
These criteria identify an absolute threshold in severity of symptoms that should be reached for clinical improvement.
This threshold value increases with the severity of COPD, because the differences between treatments in the probabilities of developing a (severe) exacerbation decrease as COPD severity increases.
These tests give a measure of the severity of sensory irritation effects of chemicals on the eye, and Draize test scores have been shown to be in good agreement with human eye irritation thresholds (Abraham et al. 2003).
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