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Bevacizumab infusions will be administered on a three-weekly basis in combination with XELOX or on a two-weekly basis in combination with mFOLFOX6 throughout Phase A treatment until first disease progression or occurrence of unmanageable toxicity.
The SAKK group performed a randomised phase II trial of 74 patients in whom all received Xelox (as used in COIN) on a three-weekly basis and half of the patients received cetuximab weekly; the toxicity data have recently been published and demonstrate a non-significant increase in grade 3/4 diarrhoea from 16 to 22%, with the addition of cetuximab (Borner et al, 2008).
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"I'll change a dish on a weekly basis.
A: They are sharing on a weekly basis.
Results showed a tumour volume increase on a weekly basis beginning with the 8th week, which is presented in graphic form in Figure 9.
Those attacks, for a time, occurred on a near-weekly basis and affected dozens of major institutions, leaving hundreds of thousands of customers unable to access their bank accounts online, the indictment alleges.
Coupang said "millions" of customers use its service at least 50 times a year, i.e. on a weekly basis.
At each of Princeton's four co-ops –– the vegetarian 2 Dickinson Street (known as 2D), Brown, International Food Co-op, and the Real Food Co-op –– students take on two-hour cooking shifts on a weekly basis, preparing meals to feed crowds that range from 12 to almost 50 people.
Oh, and also they have to watch 14th-placed West Ham on a weekly basis.
Infinite choice is nice, but judging by the fact that there are still hundreds of millions of people listening to the radio on a weekly basis, it clearly isn't what the majority of people are looking for.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com