These inhibitors exhibited improved BACE1 inhibitory activities and a thorough quantitative structure activity relationship study was performed.
Successful QbD implementation requires a thorough understanding of the relationship between the critical quality attributes (CQAs) and the clinical properties of the product, the relationship between the process and CQAs and the variability in raw materials.
This diversity also requires a thorough understanding of the relationship between these areas and how they influence network system design.
This would be followed by a thorough study of the relationship between the biopharmaceutical properties and the unique physiological attributes of the target organ, and in this case, the lung and the distinctive attributes of the pulmonary product.
The paper illustrates how a thorough understanding of the relationship between the 'static' and 'damage' components contributes to establish if damage has occurred and to provide an estimation of its location and severity.
A thorough understanding of the relationship between energy-saving techniques and disk reliability is still an open problem, which prevents effective design of new energy-saving techniques and application of existing approaches in reliability-critical environments.
A thorough analysis of structure property relationship through observing plastic deformation behaviors by scanning electron microscope (SEM) and estimating stress transmission between crystalline and amorphous phases, suggests that both MAF and RAF play important role on toughening β-PP.
"Obviously I am incredibly angry about this data breach and we will institute a thorough review of our relationship with Experian, but right now my top concern and first focus is assisting any and all consumers affected," wrote T-Mobile CEO John Legere in a blog post.
A thorough understanding of the relationship between land use temporal or spatial patterns and landscape physical parameters in the Loess Plateau of China, like degree of slope and soil type, will enhance our capability to predict landscape dynamics and lead to more sound and effective land use management strategies.
The full elucidation of the genetic influences of neurodegenerative diseases, however, requires a thorough understanding of the relationship between the variation present in our genome and the corresponding phenotypes.
However, a thorough understanding of the relationship between m6A and transcription and/or splicing awaits future investigations.
