Sentence examples for a thorough modification from inspiring English sources

Drawing on his own experience of prison life, Kropotkin also advocated a thorough modification of the penal system.

A thorough modification of the synthetic protocol, including a microwave-mediated cyclization step, allowed us to obtain 1 in 86 % overall yield even on a gram scale (Scheme  1).[ 15] The second step involved the synthesis of [ ITMe Pd methallyl Cl] (2).

They were successful enough that the Admiralty allocated £81,000 in the 1914 1915 Naval Programme to purchase a merchant ship for a more thorough modification than had been possible with Hermes to better accommodate seaplanes.

A summary of p73-interacting proteins and p73 post-translational modifications are shown in Figures 2 and 3. A thorough characterization of molecular modifications of p73 and identification of similarities between the other family members will help to fill-in the missing pieces in the p53-p73 puzzle and lead to identification of better agents for targeted tumor therapy.

Trypsin was set as the enzyme used; IAA was chosen as the cysteine alkylation agent; a thorough search with biological modifications settings, which contain a number of built-in modifications, was performed.

Briefly, the MS/MS data were analyzed by a thorough search considering biological modifications against the NCBI subset of green plants fasta database (downloaded on November, 2010) using the Paragon™ Algorithm of PROTEINPILOT v3.0 software suite (Applied Biosystems).

A thorough analysis of O-GlcNAc modification in the Oct4 interactome might yield important insight into dynamic modulation of stem cell factors.

Surface modification in nanostructures enables a thorough control on intrinsic properties, surface activity and enhancement of their usefulness in several device applications.

Proper adaptation of the instrument to the Greek norms mandated slight modification of some items and a thorough revision of the translation process that had already been performed by previous investigators.

Understandability is a key factor in determining maintainability as model modifications must be preceded by a thorough understanding of the model.

Prescribing, a complex process involving the initiation, monitoring, continuation and modification of medication therapy, 1 demands a thorough understanding of clinical pharmacology as well as the judgement and ability to prescribe rationally for the benefit of patients.