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Discover LudwigThe phrase "a thick layer of grime" is correct and usable in written English.
It can be used to describe a substantial accumulation of dirt or filth on a surface.
Example: "After months of neglect, the kitchen had developed a thick layer of grime that required hours of scrubbing to remove."
Alternatives: "a heavy coating of dirt" or "a dense film of filth."
Exact(3)
The clock still works, but splintered beams, dark water stains and a thick layer of grime are visible in the background.
Everything was covered with a thick layer of grime, from the old fashioned metal light fittings to door handles and banisters.
The pollution - a mix of local and European emissions, and dust from the Sahara - has caused a thick layer of grime to form on cars and buildings around the country.
Similar(57)
Most of the furniture was in storage and a thick layer of dust and grime coated the few items that remained: a cheap phone and an ancient computer.
Such pulsating is better left not talked about, but the guides were apparently supposed to get a subplot going involving Scott's romantic interest in Jackie, while filling in travel time with improvised dialogue and "fun facts" about the sights: the grime cleaned off the ceiling of Grand Central Terminal in 1998 was a thick layer of tar and nicotine.
Spread with a thick layer of cream.
No sugar, a thick layer of foam.
A thick layer of smog has engulfed the country.
A thick layer of scum had settled in the tub.
The key is multiple layers or a thick layer of tightly sealed air.
Both have a thick layer of provisions to draw on.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com