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By classifying the response of individual lesions, both in terms of their vascular response and change in size, we present evidence for two different forms of intrinsic resistance to anti-angiogenic therapy: (a) the adaptation of tumour cells to withdrawal of a vascular supply and (b) mechanisms that allow the tumour vasculature to survive the therapy.
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As a rule, the adaptation has a continuing nature and cannot be characterized simply as present or absent.
As a result, the adaptation effort is not blurred by unforeseeable gradient behavior.
where μ η and μ A are the adaptation step sizes, which can be adjusted experimentally.
A week later, the adaptation of David Nicholls's mega-selling novel One Day was due out.
Nature had taken a few liberties with the adaptation.
To achieve a format independent adaptation, the adaptation operation is performed on video description.
Then, to achieve a generic adaptation solution, the adaptation is developed following MPEG-21 Digital Item Adaptation (DIA) framework.
Howard, who won an Oscar for directing A Beautiful Mind, has played the adaptation game before.
a The original adaptation procedure (ACF1).
In both cases, we indicate the adaptation with a credit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com