To demonstrate the utility of the craniula technique for delivery of an inflammatory insult and tracking subsequent changes in the brain vasculature without affecting other organs, we studied the effects of three poly(ADP-ribose) type 1 (PARP-1) inhibitors in response to release of a localized inflammatory stimulus (TNFα).
A separate SIR-Spheres users' manual details the technique for delivery of the SIR-Spheres.
Emphasis is placed on the use of this technique for delivery to the liver.
Each centre applied its own technique for delivery of contrast medium, regardless of iodine concentration.
Optical transfection is a promising technique for the delivery of foreign genetic material into cells by transiently changing the permeability of the cell membrane.
Since human normal cells, e.g. fibroblasts and mesenchymal stem cells, show less efficiency of microcell fusion by PEG than malignant cells, microcell fusion mediated by MV-derived fusion machinery is an attractive technique for gene delivery which involves the transfer of a HAC vector from a donor cell to human normal cells [ 14, 19, 34].
Suprachoroidal injection is an emerging technique for drug delivery to the posterior segment, which is hard to reach by non-invasive approaches.
Mami Hamori et al. reported that electrospinning of methacrylic acid copolymer is an effective technique for drug delivery both for polar and non-polar drugs [102].
The integration of radiation therapy incorporating newer techniques for delivery and tumour targeting is currently an expanding area of investigation for patients with both operable and locally advanced disease and for the latter may offer the scope for conversion to resectable disease.
Convection-enhanced delivery (CED) is a recently developed technique for local delivery of agents to a large volume of tissue in the central nervous system (CNS).
Common techniques for delivery into cultured cells include the Endo-Porter peptide (which causes the Morpholino to be released from endosomes), the Special Delivery system (no longer commercially available, used a Morpholino-DNA heteroduplex and an ethoxylated polyethylenimine delivery reagent), electroporation, or scrape loading.
