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But the processor has a TDP of 47W and the whole thing weighs 4.8kg.
Laptop manufacturers fit low-voltage processors that generate less heat, but an airier desktop PC could use a hotter and much cheaper processor such as the 3.1GHz Pentium G3240, which has a TDP of 53W.
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"The MacBook Pro runs very hot and while the 20W TDP of the MacBook Air is significantly lower than the 35W TDP of the Pro, it's high for such a small chassis.
/*Calculate the total detection probability (TDP) of */. if then.
In the frontotemporal dementia field, Marcel Verbeek (Radboud University Medical Center, Nijmegen) presented data on optimizing and increasing the sensitivity of a TDP-43 ELISA for CSF measurement.
Of the 10 previously identified TDP-43 binding miRNAs miR-181a1-3p was omitted in this study as the effect of a TDP-43 knock-down was only marginal compared to other miRNAs [ 14].
These results are also consistent with those of Barmada et al. who recently established a TDP-43 proteinopathy model by transfecting a mutant form of TDP-43 in rat primary cortical neurons.
Prediction of 'torsadogenicity' (the likelihood of a compound initiating TdP) is of high relevance for cardiac safety assessment because, if it occurs, TdP often degenerates into ventricular arrhythmias that may cause sudden cardiac death (unless self-terminated; see Figure 1).
In case of the PM3 simulations, a simple addition of a PM ridge in addition to a PM bridge gave TdP type of excitation patterns.
The presence of lower molecular weight species comprising the C-terminal region of TAR DNA-binding protein 43 (TDP-43) is a characteristic of TDP-43 proteinopathy in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).
To achieve this, we generated expression constructs for a series of TDP-43 variants, including TDP-43WT, synthetic mutants (TDP-43SM) and ALS/FTLD-linked TDP-43MS (Fig. 1A).
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