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This contribution focuses on the development of a targeting approach, for which a new distributive reaction-mixing synthesis model is formulated and applied.
This subcloned genomic region was then modified in a targeting approach using the neo cassettes from the PL452 vector.
A targeting approach would extend the possibility of therapeutic correction to both recessive and dominant diseases [ 2].
A targeting approach that might be worthwhile to explore in this context is patient-mediated cascading, as is used in screening for familial hypercholesterolemia [ 17].
Finally, many of the nanoparticle-based medicines in development consider a targeting approach to a particular receptor or protein that may be expressed, e.g., by tumors.
To this end, there was some evidence for the acceptability and feasibility of using a targeting approach based on a flexible menu of strategies in which the practitioner and patient select a topic according to need [ 31, 33].
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This was "not simply aspirational marking" by paper or unit but a "targeted approach to the whole GCSE", she said.
A new kind of cancer therapy, it was tailored to a particular genetic mutation that was driving the disease, and after six years of disappointments his faith in the promise of such a "targeted" approach finally seemed borne out.
So even when I do an approach that is really targeted I know there are a hundred other people trying a targeted approach as well".
100 A number of groups have tried to apply a targeted approach to glaucoma screening using teleglaucoma.
We have therefore chosen to generate a more accurate model of the human disease via a gene targeting approach, by introducing a point mutation into the endogenous promoter.
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