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Discover LudwigThe phrase "a targeted modification of" is correct and usable in written English.
It can be used when discussing specific changes or adjustments made to something with a particular goal in mind.
Example: "The researchers implemented a targeted modification of the genetic sequence to enhance the plant's resistance to disease."
Alternatives: "a specific alteration of" or "a focused adjustment of".
Exact(1)
Remarkably, these mouse strains, which bear a targeted modification of Lhx4 in the heterozygous state, are asymptomatic, whereas homozygous animals die shortly after birth.
Similar(59)
We therefore performed a targeted modification screen of these enhancer promoter (EP -element insEP -elements for abinsertionmodulinesthe CAG-repeat RNA toxicity.
To exclude the latter hypothesis and to check the accessibility for recombination of the PfI2 locus, we introduced a targeted modification in the locus without loss-of-function.
A series of novel coumarin derivatives were rationally designed and synthesized by use of a complex catalytic system for a targeted modification at the above sites.
On the other hand, measurement of gene editing at the single cell level, employed assays for targeted modification of a mutated GFP.
A special apparatus allowing for the targeted modification of the physicochemical characteristics of dispersive systems via a self-organised liquid flow (Bénard-Marangoni or Railegh-Bénard instability) was constructed.
Modern genome engineering technologies have made the targeted modification of human genes possible for a multitude of therapeutic applications.
Recent advances in the targeted modification of complex eukaryotic genomes have unlocked a new era of genome engineering.
Another future goal is the targeted modification of the murine stroma to achieve a more human-like appearance without compromising the normal function of the gland.
Combination of systemic induction of antigen-specific immune response with LCP vaccine and targeted modification of tumor microenvironment with LPH NP offers a flexible and powerful platform for both mechanism study and immunotherapeutic strategy development.
An alternative, and more widely investigated, strategy for the targeted modification of plant genomes is the production of a DNA break at a unique chromosomal location using a site-specific endonuclease that recognizes a relatively long, and therefore unique, DNA sequence.
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