Sentence examples for a targeted modification from inspiring English sources
A series of novel coumarin derivatives were rationally designed and synthesized by use of a complex catalytic system for a targeted modification at the above sites.
Remarkably, these mouse strains, which bear a targeted modification of Lhx4 in the heterozygous state, are asymptomatic, whereas homozygous animals die shortly after birth.
Moreover a targeted modification at exact positions within a genomic BAC clone can be introduced by recombineering [ 15, 16].
We therefore performed a targeted modification screen of these enhancer promoter (EP -element insEP -elements for abinsertionmodulinesthe CAG-repeat RNA toxicity.
To exclude the latter hypothesis and to check the accessibility for recombination of the PfI2 locus, we introduced a targeted modification in the locus without loss-of-function.
The knock-in approach used here results in a well-defined targeted modification that is therefore more precise and less prone to induction of artefacts.
Engineered zinc finger nuclease (ZFN mediated genetic modification in somatic cells combined with somatic cell nuclear transfer (SCNT) technology provides a new approach for targeted modification in pig genome.
A brief investigation on the structure activity relationships (SAR) revealed that the targeted modification by a C7 hydroxyl was optimum compared with that of a C4 hydroxyl and that the coupling chain length was crucial for the nematicidal activity.
On the other hand, measurement of gene editing at the single cell level, employed assays for targeted modification of a mutated GFP.
A special apparatus allowing for the targeted modification of the physicochemical characteristics of dispersive systems via a self-organised liquid flow (Bénard-Marangoni or Railegh-Bénard instability) was constructed.
Of these mechanisms, Na+ exclusion from the shoot is best understood and is, therefore, the current best candidate for a targeted genetic modification approach to improving salinity tolerance.
