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The declassified letters said the collection efforts "significantly strengthen" the discovery of terrorists and their plots; the agency has previously claimed that 54 plots were disrupted by the collection of phone records and a separate, targeted collection of Internet data.
What looks like targeted collection under a program like Prism may simply be the final step in a process that, considered as a whole, employs specific target identifiers as an intermediary step in what is functionally algorithmic or pattern-based surveillance.
The intelligence community no doubt regards targeted collection methods like TAO as a method of last resort, to be used only when mass surveillance fails.
We need to move to the targeted collection codified by the USA Freedom Act without any delay".
But it also embraces experimentation, selling a Target collection by Proenza Schouler one weekend last year; a line by the actress Chloë Sevigny last month; and, since 2005, the fast-fashion Topshop label.
Patients achieving complete remission (CR) or partial remission (PR) after 2 to 4 courses of reinduction underwent a granulocyte-colony stimulating factor (G-CSF) mobilized PBSC apheresis with a target collection dose of 5 × 106 CD34+/kg.
Sound a little pricey for a Target collection?
For patients with NHL or HD, a PB-CD34 <6/uL and <15/uL on day 4 or 5 predicted failure to achieve a target collection of 2 and 4 million/kg respectively.
When the WBC count exceeded 10 × 10/L, the MNC count exceeded 2 × 10/L, and the percentage of CD34+ cells in peripheral blood exceeded 1% [ 18], continuous APBSC collection was conducted daily with a CS-3000 Plus blood cell separator (Baxter Healthcare Corp., Deerfield, IL, USA) until a target collection of at least 2 × 10 cells/kglls/kg body weight or 4 × 10 MNCs/kg body weight was achieved.
The use of routine data rather than a targeted data collection could have caused more random error resulting in type II error.
Similar steps include preparing data (compounds in a formula, target collection or prediction for a formula, disease proteins and therapeutic targets or proteins involved in disease-related pathways, and protein-protein interaction (PPI) data), analyzing networks and discovering the potential pathways or processes that the formula affects to cure a specific disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com