Sentence examples for a target for mediating from inspiring English sources

This raises the possibility that RanBPM could be a target for mediating the actions of secreted psoriasin, perhaps affecting T cell trafficking to activated or inflamed sites.

Being the basis of natural pathways for tissue maintenance and repair, stem cells represent a key target for mediating repair in vivo.

In this study, we showed that non-immune tissue cells like fibroblasts, which are much safer for ML survival than macrophages and are widely distributed (in the absence of inflammation) in peripheral nerves and skin, two preferred tissue niches for ML, are a likely target for mediating bacterial dissemination.

These findings implicate Drp1 as a potential therapeutic target for mediating DA closure (see Figure 2).

Furthermore, we demonstrate that NAMPT is the relevant target for mediating the effects of STF-31-like small molecules on cancer cell viability through the use of unbiased NGS-based genomic biomarker identification strategies to uncover a recurrent mutation within NAMPT (H191R) that is sufficient to render cells resistant to STF-31 and compound 146.

In recent developments we have also shown that ETR1 has a dual function in guard cells, that of perceiving ethylene as well as acting as a target for H2O2, thereby mediating downstream signalling processes to initiate stomatal closure [16].

A number of novel therapeutic targets for mediating cardiovascular protection in relation to a number of conditions including acute ischemia/reperfusion, heart failure, and atherosclerosis were introduced at the meeting.

In addition, autologous DPSCs are as good of a target for NK cell mediated lysis as the allogeneic DPSCs.

Here we show that FLRT1 is a target for tyrosine phosphorylation mediated by FGFR1 and implicate a non-receptor Src family kinase (SFK).

E2 antagonizes Runx2-induced EMT and invasiveness of BCa cells, partly through attenuating expression of SNAI2, a Runx2 target required for mediating its pro-metastatic property.

Therefore, we selected the PKC and MAPK pathways as targets for mediating the stimulatory effects of EA on gastric mobility.